Will your local print shop help you setup your own online point of sale? Or take care of all shipping duties when a customer orders it online. Sorry I do not see the comparison.
Cafepress has a major hub here in Louisville b/c UPS has a major hub here. Shipping is very quick. I went out and visited their facility. They do not use screen printing. They use a proprietary printing process that uses some form of ink jet printing. It works great lasts a long time. With maybe an hour of set up and uploading of images we had a store front online that all we had to do was check the mailbox for our cut of the sales. Literally that easy.
COO / Zymurgist
Goodwood Brewing Co
636 East Main St