I'd say use some common sense. Tongue in cheek is par for the course in this business, as the word "Bitch" comes to mind as being used quite a bit. As far as the legality, you will find out from your local jurisdiction if it's gonna fly. Just be cautious of "offending" any race/color/creed/sexual orientation, and you should be fine, but broad spectrum marketing may be effected. My 2 cents.
Triplehorn Brewing Co.